Cargando…

Homology modeling and molecular docking simulation of martentoxin as a specific inhibitor of the BK channel

BACKGROUND: Large conductance calcium-activated potassium channel (BK channel) is gated by both voltage and calcium ions and is widely distributed in excitable and nonexcitable cells. BK channel plays an important role in epilepsy and other diseases, but BK channel subtype-specific drugs are still e...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Chao, Yang, Zihao, Tong, Kuiyuan, Wang, Jiawei, Yang, Wanli, Yu, Ruihua, Jiang, Feng, Ji, Yonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848368/
https://www.ncbi.nlm.nih.gov/pubmed/35282126
http://dx.doi.org/10.21037/atm-21-6967