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Asiaticoside alleviates cardiomyocyte apoptosis and oxidative stress in myocardial ischemia/reperfusion injury via activating the PI3K-AKT-GSK3β pathway in vivo and in vitro

BACKGROUND: Myocardial ischemia/reperfusion (MI/R) is one of the most important links in myocardial injury, causing damage to cardiac tissues including cell apoptosis, oxidative stress, and other serious consequences. Asiaticoside (AS), a new compound synthesized from genistein, is cardioprotective....

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Detalles Bibliográficos
Autores principales: Zeng, Xueliang, Yu, Junjian, Liu, Peipei, Liu, Yuan, Zeng, Taohui, Li, Bei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848378/
https://www.ncbi.nlm.nih.gov/pubmed/35282120
http://dx.doi.org/10.21037/atm-21-6667