Genistein mitigates oxidative stress and inflammation by regulating Nrf2/HO-1 and NF-κB signaling pathways in hypoxic-ischemic brain damage in neonatal mice

BACKGROUND: Oxidative stress and neuroinflammation play crucial roles in the progression of neonatal hypoxic-ischemic brain damage (HIBD). Genistein, a natural phytoestrogen, has been found to protect against ischemic brain injury. However, its effects and potential mechanisms in HIBD have not yet b...

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Detalles Bibliográficos
Autores principales: Li, Yuan, Zhang, Jin-Jia, Chen, Ru-Jia, Chen, Ling, Chen, Su, Yang, Xiao-Fei, Min, Jia-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848430/
https://www.ncbi.nlm.nih.gov/pubmed/35282070
http://dx.doi.org/10.21037/atm-21-4958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848430/
https://www.ncbi.nlm.nih.gov/pubmed/35282070
http://dx.doi.org/10.21037/atm-21-4958

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