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Ruxolitinib attenuates secondary injury after traumatic spinal cord injury

Excessive inflammation post-traumatic spinal cord injury (SCI) induces microglial activation, which leads to prolonged neurological dysfunction. However, the mechanism underlying microglial activation-induced neuroinflammation remains poorly understood. Ruxolitinib (RUX), a selective inhibitor of JA...

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Detalles Bibliográficos
Autores principales: Qian, Zhan-Yang, Kong, Ren-Yi, Zhang, Sheng, Wang, Bin-Yu, Chang, Jie, Cao, Jiang, Wu, Chao-Qin, Huang, Zi-Yan, Duan, Ao, Li, Hai-Jun, Yang, Lei, Cao, Xiao-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848590/
https://www.ncbi.nlm.nih.gov/pubmed/35142693
http://dx.doi.org/10.4103/1673-5374.335165