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(D-Ser2) oxyntomodulin recovers hippocampal synaptic structure and theta rhythm in Alzheimer's disease transgenic mice

In our previous studies, we have shown that (D-Ser2) oxyntomodulin (Oxm), a glucagon-like peptide 1 (GLP-1) receptor (GLP1R)/glucagon receptor (GCGR) dual agonist peptide, protects hippocampal neurons against Aβ(1–42) -induced cytotoxicity, and stabilizes the calcium homeostasis and mitochondrial me...

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Detalles Bibliográficos
Autores principales: Yang, Guang-Zhao, Gao, Qi-Chao, Li, Wei-Ran, Cai, Hong-Yan, Zhao, Hui-Min, Wang, Jian-Ji, Zhao, Xin-Rui, Wang, Jia-Xin, Wu, Mei-Na, Zhang, Jun, Hölscher, Christian, Qi, Jin-Shun, Wang, Zhao-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848598/
https://www.ncbi.nlm.nih.gov/pubmed/35142699
http://dx.doi.org/10.4103/1673-5374.335168