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Functional genomics elucidates regulatory mechanisms of Parkinson’s disease-associated variants

BACKGROUND: Genome-wide association studies (GWASs) have identified multiple risk loci for Parkinson’s disease (PD). However, identifying the functional (or potential causal) variants in the reported risk loci and elucidating their roles in PD pathogenesis remain major challenges. To identify the po...

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Detalles Bibliográficos
Autores principales: Chen, Rui, Liu, Jiewei, Li, Shiwu, Li, Xiaoyan, Huo, Yongxia, Yao, Yong-Gang, Xiao, Xiao, Li, Ming, Luo, Xiong-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848643/
https://www.ncbi.nlm.nih.gov/pubmed/35168626
http://dx.doi.org/10.1186/s12916-022-02264-w