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Impaired TRPM3-dependent calcium influx and restoration using Naltrexone in natural killer cells of myalgic encephalomyelitis/chronic fatigue syndrome patients

BACKGROUND: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a serious disorder of unknown aetiology. While the pathomechanism of ME/CFS remains elusive, reduced natural killer (NK) cell cytotoxic function is a consistent immunological feature. NK cell effector functions rely on long-t...

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Detalles Bibliográficos
Autores principales: Eaton-Fitch, Natalie, Du Preez, Stanley, Cabanas, Hélène, Muraki, Katsuhiko, Staines, Donald, Marshall-Gradisnik, Sonya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848670/
https://www.ncbi.nlm.nih.gov/pubmed/35172836
http://dx.doi.org/10.1186/s12967-022-03297-8