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The Role of Mitochondria-Linked Fatty-Acid Uptake-Driven Adipogenesis in Graves Orbitopathy

CONTEXT: Depot-specific expansion of orbital adipose tissue (OAT) in Graves orbitopathy (GO; an autoimmune condition producing proptosis, visual impairment and reduced quality of life) is associated with fatty acid (FA)-uptake–driven adipogenesis in preadipocytes/fibroblasts (PFs). OBJECTIVE: This w...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Rai, Pavandeep, Miwa, Satomi, Draman, Mohd Shazli, Rees, D Aled, Haridas, Anjana S, Morris, Daniel S, Tee, Andrew R, Ludgate, Marian, Turnbull, Doug M, Dayan, Colin M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848742/
https://www.ncbi.nlm.nih.gov/pubmed/34473251
http://dx.doi.org/10.1210/endocr/bqab188