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Establishment of an orthotopic prostate cancer xenograft mouse model using microscope-guided orthotopic injection of LNCaP cells into the dorsal lobe of the mouse prostate

BACKGROUND: Orthotopic LNCaP xenograft mouse models closely mimic the progression of androgen-dependent prostate cancer in humans; however, orthotopic injection of LNCaP cells into the mouse prostate remains a challenge. METHODS: Under the guidance of a stereoscopic microscope, the anatomy of the in...

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Detalles Bibliográficos
Autores principales: Liu, Weiyong, Zhu, Yunkai, Ye, Lei, Zhu, Yajuan, Wang, Yuhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848828/
https://www.ncbi.nlm.nih.gov/pubmed/35168543
http://dx.doi.org/10.1186/s12885-022-09266-0