CROPSR: an automated platform for complex genome-wide CRISPR gRNA design and validation

BACKGROUND: CRISPR/Cas9 technology has become an important tool to generate targeted, highly specific genome mutations. The technology has great potential for crop improvement, as crop genomes are tailored to optimize specific traits over generations of breeding. Many crops have highly complex and p...

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Detalles Bibliográficos
Autores principales: Müller Paul, Hans, Istanto, Dave D., Heldenbrand, Jacob, Hudson, Matthew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848901/
https://www.ncbi.nlm.nih.gov/pubmed/35172714
http://dx.doi.org/10.1186/s12859-022-04593-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848901/
https://www.ncbi.nlm.nih.gov/pubmed/35172714
http://dx.doi.org/10.1186/s12859-022-04593-2

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