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CROPSR: an automated platform for complex genome-wide CRISPR gRNA design and validation
BACKGROUND: CRISPR/Cas9 technology has become an important tool to generate targeted, highly specific genome mutations. The technology has great potential for crop improvement, as crop genomes are tailored to optimize specific traits over generations of breeding. Many crops have highly complex and p...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848901/ https://www.ncbi.nlm.nih.gov/pubmed/35172714 http://dx.doi.org/10.1186/s12859-022-04593-2 |