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Development of an RNA–protein crosslinker to capture protein interactions with diverse RNA structures in cells
Characterization of RNA–protein interaction is fundamental for understanding the metabolism and function of RNA. UV crosslinking has been widely used to map the targets of RNA-binding proteins, but is limited by low efficiency, requirement for zero-distance contact, and biases for single-stranded RN...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848928/ https://www.ncbi.nlm.nih.gov/pubmed/34916333 http://dx.doi.org/10.1261/rna.078896.121 |