Development of an RNA–protein crosslinker to capture protein interactions with diverse RNA structures in cells

Characterization of RNA–protein interaction is fundamental for understanding the metabolism and function of RNA. UV crosslinking has been widely used to map the targets of RNA-binding proteins, but is limited by low efficiency, requirement for zero-distance contact, and biases for single-stranded RN...

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Detalles Bibliográficos
Autores principales: Han, Yan, Guo, Xuzhen, Zhang, Tiancai, Wang, Jiangyun, Ye, Keqiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848928/
https://www.ncbi.nlm.nih.gov/pubmed/34916333
http://dx.doi.org/10.1261/rna.078896.121

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