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A versatile tRNA modification-sensitive northern blot method with enhanced performance

The 22 mitochondrial and ∼45 cytosolic tRNAs in human cells contain several dozen different post-transcriptional modified nucleotides such that each carries a unique constellation that complements its function. Many tRNA modifications are linked to altered gene expression, and deficiencies due to mu...

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Detalles Bibliográficos
Autores principales: Khalique, Abdul, Mattijssen, Sandy, Maraia, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848930/
https://www.ncbi.nlm.nih.gov/pubmed/34930808
http://dx.doi.org/10.1261/rna.078929.121