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Tollip interaction with STAT3: a novel mechanism to regulate human airway epithelial responses to type 2 cytokines

BACKGROUND: Toll-interacting protein (Tollip) is one of the key negative regulators in host innate immunity. Genetic variation of Tollip has been associated with less Tollip expression and poor lung function in asthmatic patients, but little is known about the role of Tollip in human airway type 2 i...

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Detalles Bibliográficos
Autores principales: Schaunaman, Niccolette, Dimasuay, Kris Genelyn, Kraft, Monica, Chu, Hong Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848971/
https://www.ncbi.nlm.nih.gov/pubmed/35172835
http://dx.doi.org/10.1186/s12931-022-01941-x