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High-Titer Neutralizing Antibodies against the SARS-CoV-2 Delta Variant Induced by Alhydroxyquim-II-Adjuvanted Trimeric Spike Antigens

Global control of COVID-19 will require the deployment of vaccines capable of inducing long-term protective immunity against SARS-CoV-2 variants. In this report, we describe an adjuvanted subunit candidate vaccine that affords elevated, sustained, and cross-variant SARS-CoV-2 neutralizing antibodies...

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Detalles Bibliográficos
Autores principales: Counoupas, Claudio, Pino, Paco, Stella, Alberto O., Ashley, Caroline, Lukeman, Hannah, Bhattacharyya, Nayan D., Tada, Takuya, Anchisi, Stephanie, Metayer, Charles, Martinis, Jacopo, Aggarwal, Anupriya, Dcosta, Belinda M., Britton, Warwick J., Kint, Joeri, Wurm, Maria J., Landau, Nathaniel R., Steain, Megan, Turville, Stuart G., Wurm, Florian M., David, Sunil A., Triccas, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8849074/
https://www.ncbi.nlm.nih.gov/pubmed/35171046
http://dx.doi.org/10.1128/spectrum.01695-21