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High-Titer Neutralizing Antibodies against the SARS-CoV-2 Delta Variant Induced by Alhydroxyquim-II-Adjuvanted Trimeric Spike Antigens
Global control of COVID-19 will require the deployment of vaccines capable of inducing long-term protective immunity against SARS-CoV-2 variants. In this report, we describe an adjuvanted subunit candidate vaccine that affords elevated, sustained, and cross-variant SARS-CoV-2 neutralizing antibodies...
Autores principales: | Counoupas, Claudio, Pino, Paco, Stella, Alberto O., Ashley, Caroline, Lukeman, Hannah, Bhattacharyya, Nayan D., Tada, Takuya, Anchisi, Stephanie, Metayer, Charles, Martinis, Jacopo, Aggarwal, Anupriya, Dcosta, Belinda M., Britton, Warwick J., Kint, Joeri, Wurm, Maria J., Landau, Nathaniel R., Steain, Megan, Turville, Stuart G., Wurm, Florian M., David, Sunil A., Triccas, James A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8849074/ https://www.ncbi.nlm.nih.gov/pubmed/35171046 http://dx.doi.org/10.1128/spectrum.01695-21 |
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