Chronic paternal morphine exposure increases sensitivity to morphine-derived pain relief in male progeny

Parental history of opioid exposure is seldom considered when prescribing opioids for pain relief. To explore whether parental opioid exposure may affect sensitivity to morphine in offspring, we developed a “rat pain scale” with high-speed imaging, machine learning, and mathematical modeling in a mu...

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Detalles Bibliográficos
Autores principales: Toussaint, Andre B., Foster, William, Jones, Jessica M., Kaufmann, Samuel, Wachira, Meghan, Hughes, Robert, Bongiovanni, Angela R., Famularo, Sydney T., Dunham, Benjamin P., Schwark, Ryan, Karbalaei, Reza, Dressler, Carmen, Bavley, Charlotte C., Fried, Nathan T., Wimmer, Mathieu E., Abdus-Saboor, Ishmail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8849295/
https://www.ncbi.nlm.nih.gov/pubmed/35171664
http://dx.doi.org/10.1126/sciadv.abk2425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8849295/
https://www.ncbi.nlm.nih.gov/pubmed/35171664
http://dx.doi.org/10.1126/sciadv.abk2425

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