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A test of the pioneer factor hypothesis using ectopic liver gene activation

The pioneer factor hypothesis (PFH) states that pioneer factors (PFs) are a subclass of transcription factors (TFs) that bind to and open inaccessible sites and then recruit non-pioneer factors (non-PFs) that activate batteries of silent genes. The PFH predicts that ectopic gene activation requires...

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Detalles Bibliográficos
Autores principales: Hansen, Jeffrey L, Loell, Kaiser J, Cohen, Barak A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8849321/
https://www.ncbi.nlm.nih.gov/pubmed/34984978
http://dx.doi.org/10.7554/eLife.73358