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Fibroblast mechanotransduction network predicts targets for mechano-adaptive infarct therapies

Regional control of fibrosis after myocardial infarction is critical for maintaining structural integrity in the infarct while preventing collagen accumulation in non-infarcted areas. Cardiac fibroblasts modulate matrix turnover in response to biochemical and biomechanical cues, but the complex inte...

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Detalles Bibliográficos
Autores principales: Rogers, Jesse D, Richardson, William J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8849334/
https://www.ncbi.nlm.nih.gov/pubmed/35138248
http://dx.doi.org/10.7554/eLife.62856