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P07 Toxicokinetic profile of VRP-034

BACKGROUND: Polymyxin B (PMB) can be an effective option for treating resistant Gram-negative pathogens, however, its use is severely compromised by its’ dose-limiting toxicity. VRP-034, a novel formulation of PMB, has previously reported a favourable safety profile compared with marketed PMB (Roy e...

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Detalles Bibliográficos
Autores principales: Murkunde, Yogeshkumar Vishnupant, Chaudhary, Saransh, Vishwakarma, Kamlesh Kumar, Aggarwal, Anmol, Chilbule, Rahul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8849398/
http://dx.doi.org/10.1093/jacamr/dlac004.006