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Scalable manufacturing platform for the production of methemoglobin as a non-oxygen carrying control material in studies of cell-free hemoglobin solutions
Methemoglobin (metHb) arises from the oxidation of ferrous hemoglobin (HbFe(2+), Hb) to ferric hemoglobin (HbFe(3+), metHb), which is unable to bind gaseous ligands such as oxygen (O(2)) and carbon monoxide (CO), and binds to nitric oxide (NO) significantly slower compared to Hb. Therefore, metHb do...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8849478/ https://www.ncbi.nlm.nih.gov/pubmed/35171971 http://dx.doi.org/10.1371/journal.pone.0263782 |