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Scalable manufacturing platform for the production of methemoglobin as a non-oxygen carrying control material in studies of cell-free hemoglobin solutions

Methemoglobin (metHb) arises from the oxidation of ferrous hemoglobin (HbFe(2+), Hb) to ferric hemoglobin (HbFe(3+), metHb), which is unable to bind gaseous ligands such as oxygen (O(2)) and carbon monoxide (CO), and binds to nitric oxide (NO) significantly slower compared to Hb. Therefore, metHb do...

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Detalles Bibliográficos
Autores principales: Gu, Xiangming, Hickey, Richard, Rath, Antara, Palmer, Andre F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8849478/
https://www.ncbi.nlm.nih.gov/pubmed/35171971
http://dx.doi.org/10.1371/journal.pone.0263782