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Scalable manufacturing platform for the production of methemoglobin as a non-oxygen carrying control material in studies of cell-free hemoglobin solutions
Methemoglobin (metHb) arises from the oxidation of ferrous hemoglobin (HbFe(2+), Hb) to ferric hemoglobin (HbFe(3+), metHb), which is unable to bind gaseous ligands such as oxygen (O(2)) and carbon monoxide (CO), and binds to nitric oxide (NO) significantly slower compared to Hb. Therefore, metHb do...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8849478/ https://www.ncbi.nlm.nih.gov/pubmed/35171971 http://dx.doi.org/10.1371/journal.pone.0263782 |