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In silico investigations of heparin binding to SARS‐CoV‐2 variants with a focus at the RBD/ACE2 interface

The increased infectivity and transmissibility of SARS‐CoV‐2 new variants were contributed largely by increase binding of receptor binding domain (RBD) domain of the Spike (S) protein to its cellular receptor ACE2 (Angiotensin-Converting Enzyme 2). Several studies have indicated that heparin and its...

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Detalles Bibliográficos
Autores principales: Ali, Nemat, Khan, Rehan, AlAsmari, Abdullah F., Kumar, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8849831/
https://www.ncbi.nlm.nih.gov/pubmed/35194375
http://dx.doi.org/10.1016/j.procbio.2022.02.012