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Rapid detection and tracking of Omicron variant of SARS-CoV-2 using CRISPR-Cas12a-based assay

BACKGROUND: The newly emerged SARS-CoV-2 variant of concern (VOC) Omicron is spreading quickly worldwide, which manifests an urgent need of simple and rapid assay to detect and diagnose Omicron infection and track its spread. METHODS: To design allele-specific CRISPR RNAs (crRNAs) targeting the sign...

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Detalles Bibliográficos
Autores principales: Liang, Yuanhao, Lin, Hongqing, Zou, Lirong, Deng, Xiaoling, Tang, Shixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8849905/
https://www.ncbi.nlm.nih.gov/pubmed/35189535
http://dx.doi.org/10.1016/j.bios.2022.114098