Endoplasmic Reticulum Stress in Colonic Mucosa of Ulcerative Colitis Patients Is Mediated by PERK and IRE1 Pathway Activation

Ulcerative colitis (UC) is characterized by a chronic overproduction of proinflammatory cytokines. During an acute phase, the endoplasmic reticulum (ER) is overloaded and the protein folding process is impaired, a condition named ER stress. This state induces a response (unfolded protein response (U...

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Detalles Bibliográficos
Autores principales: Rodrigues, Bruno Lima, Dotti, Isabella, Pascoal, Lívia Bitencourt, Morari, Joseane, Esteller, Miriam, Coope, Andressa, Ayrizono, Maria de Lourdes Setsuko, Salas, Azucena, Leal, Raquel Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8849912/
https://www.ncbi.nlm.nih.gov/pubmed/35185383
http://dx.doi.org/10.1155/2022/6049500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8849912/
https://www.ncbi.nlm.nih.gov/pubmed/35185383
http://dx.doi.org/10.1155/2022/6049500

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