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The use of Bayesian methodology in the development and validation of a tiered assessment approach towards prediction of rat acute oral toxicity
There exists consensus that the traditional means by which safety of chemicals is assessed—namely through reliance upon apical outcomes obtained following in vivo testing—is increasingly unfit for purpose. Whilst efforts in development of suitable alternatives continue, few have achieved levels of r...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850222/ https://www.ncbi.nlm.nih.gov/pubmed/35034154 http://dx.doi.org/10.1007/s00204-021-03205-x |