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Tetramethylpyrazine Alleviates Endothelial Glycocalyx Degradation and Promotes Glycocalyx Restoration via TLR4/NF-κB/HPSE1 Signaling Pathway During Inflammation

Tetramethylpyrazine (TMP), a Chinese traditional herbal extraction widely used in treating cardiovascular diseases, could attenuate vascular endothelial injuries, but the underlying mechanism remains incomprehensive. Vascular glycocalyx coating on the endothelium would be damaged and caused endothel...

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Detalles Bibliográficos
Autores principales: Lei, Jin, Xiang, Peng, Zeng, Shengmei, Chen, Le, Zhang, Lei, Yuan, Zhiyi, Zhang, Jun, Wang, Tingting, Yu, Ruihong, Zhang, Wanping, Ibrahim, Issa Issoufou, Ma, Limei, Yu, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850260/
https://www.ncbi.nlm.nih.gov/pubmed/35185540
http://dx.doi.org/10.3389/fphar.2021.791841