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CD44-Mediated Poor Prognosis in Glioma Is Associated With M2-Polarization of Tumor-Associated Macrophages and Immunosuppression

BACKGROUND: Glioma is the most common primary brain tumor with a poor prognosis. Key genes that are negatively related to prognosis may provide the therapy targets to cure glioma. To clarify the role of CD44 in glioma, we explored its function at bulk-transcriptome, spatial and single-cell transcrip...

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Detalles Bibliográficos
Autores principales: Xiao, Yong, Yang, Kun, Wang, Zhen, Zhao, Mengjie, Deng, Yanxiang, Ji, Wei, Zou, Yuanjie, Qian, Chunfa, Liu, Yong, Xiao, Hong, Liu, Hongyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850306/
https://www.ncbi.nlm.nih.gov/pubmed/35187044
http://dx.doi.org/10.3389/fsurg.2021.775194