Early alveolar macrophage response and IL-1R-dependent T cell priming determine transmissibility of Mycobacterium tuberculosis strains

Mechanisms underlying variability in transmission of Mycobacterium tuberculosis strains remain undefined. By characterizing high and low transmission strains of M.tuberculosis in mice, we show here that high transmission M.tuberculosis strain induce rapid IL-1R-dependent alveolar macrophage migratio...

Descripción completa

Detalles Bibliográficos
Autores principales: Lovey, Arianne, Verma, Sheetal, Kaipilyawar, Vaishnavi, Ribeiro-Rodrigues, Rodrigo, Husain, Seema, Palaci, Moises, Dietze, Reynaldo, Ma, Shuyi, Morrison, Robert D., Sherman, David. R., Ellner, Jerrold J., Salgame, Padmini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850437/
https://www.ncbi.nlm.nih.gov/pubmed/35173157
http://dx.doi.org/10.1038/s41467-022-28506-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850437/
https://www.ncbi.nlm.nih.gov/pubmed/35173157
http://dx.doi.org/10.1038/s41467-022-28506-2

Ejemplares similares