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mRNA vaccine-induced antibodies more effective than natural immunity in neutralizing SARS-CoV-2 and its high affinity variants

Several variants of SARS-CoV-2 have emerged. Those with mutations in the angiotensin-converting enzyme (ACE2) receptor binding domain (RBD) are associated with increased transmission and severity. In this study, we developed both antibody quantification and functional neutralization assays. Analyses...

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Detalles Bibliográficos
Autores principales: Yu, Yunkai, Esposito, Dominic, Kang, Zhigang, Lu, Jianming, Remaley, Alan T., De Giorgi, Valeria, Chen, Leonard N., West, Kamille, Cao, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850441/
https://www.ncbi.nlm.nih.gov/pubmed/35173254
http://dx.doi.org/10.1038/s41598-022-06629-2