The AUTOTAC chemical biology platform for targeted protein degradation via the autophagy-lysosome system

Targeted protein degradation allows targeting undruggable proteins for therapeutic applications as well as eliminating proteins of interest for research purposes. While several degraders that harness the proteasome or the lysosome have been developed, a technology that simultaneously degrades target...

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Detalles Bibliográficos
Autores principales: Ji, Chang Hoon, Kim, Hee Yeon, Lee, Min Ju, Heo, Ah Jung, Park, Daniel Youngjae, Lim, Sungsu, Shin, Seulgi, Ganipisetti, Srinivasrao, Yang, Woo Seung, Jung, Chang An, Kim, Kun Young, Jeong, Eun Hye, Park, Sun Ho, Bin Kim, Su, Lee, Su Jin, Na, Jeong Eun, Kang, Ji In, Chi, Hyung Min, Kim, Hyun Tae, Kim, Yun Kyung, Kim, Bo Yeon, Kwon, Yong Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850458/
https://www.ncbi.nlm.nih.gov/pubmed/35173167
http://dx.doi.org/10.1038/s41467-022-28520-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850458/
https://www.ncbi.nlm.nih.gov/pubmed/35173167
http://dx.doi.org/10.1038/s41467-022-28520-4

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