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Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression

The formation of pre-metastatic niche is a key step in the metastatic burden. The pluripotent factor Lin28B is frequently expressed in breast tumors and is particularly upregulated in the triple negative breast cancer subtype. Here, we demonstrate that Lin28B promotes lung metastasis of breast cance...

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Detalles Bibliográficos
Autores principales: Qi, Meiyan, Xia, Yun, Wu, Yanjun, Zhang, Zhuo, Wang, Xinyu, Lu, Liying, Dai, Cheng, Song, Yanan, Xu, Keying, Ji, Weiwei, Zhan, Lixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850492/
https://www.ncbi.nlm.nih.gov/pubmed/35173168
http://dx.doi.org/10.1038/s41467-022-28438-x