Mono-ADP-ribosylation sites of human CD73 inhibit its adenosine-generating enzymatic activity

CD73-derived adenosine plays a major role in damage-induced tissue responses by inhibiting inflammation. Damage-associated stimuli, such as hypoxia and mechanical stress, induce the cellular release of ATP and NAD(+) and upregulate the expression of the nucleotide-degrading purinergic ectoenzyme cas...

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Detalles Bibliográficos
Autores principales: Hesse, Julia, Rosse, Mona K., Steckel, Bodo, Blank-Landeshammer, Bernhard, Idel, Svenja, Reinders, Yvonne, Sickmann, Albert, Sträter, Norbert, Schrader, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850506/
https://www.ncbi.nlm.nih.gov/pubmed/34961895
http://dx.doi.org/10.1007/s11302-021-09832-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850506/
https://www.ncbi.nlm.nih.gov/pubmed/34961895
http://dx.doi.org/10.1007/s11302-021-09832-4

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