Cargando…
Mono-ADP-ribosylation sites of human CD73 inhibit its adenosine-generating enzymatic activity
CD73-derived adenosine plays a major role in damage-induced tissue responses by inhibiting inflammation. Damage-associated stimuli, such as hypoxia and mechanical stress, induce the cellular release of ATP and NAD(+) and upregulate the expression of the nucleotide-degrading purinergic ectoenzyme cas...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850506/ https://www.ncbi.nlm.nih.gov/pubmed/34961895 http://dx.doi.org/10.1007/s11302-021-09832-4 |