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Therapeutic effects of mesenchymal stem cells loaded with oncolytic adenovirus carrying decorin on a breast cancer lung metastatic mouse model

Oncolytic adenoviruses (OAds) are alternative immune therapeutic strategies for tumors. However, liver uptake and antibody neutralization are two major barriers for systemic delivery during the treatment of tumor metastasis. Mesenchymal stem cells (MSCs) have emerged as potential vehicles to improve...

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Detalles Bibliográficos
Autores principales: Zhang, Yuning, Liu, Chao, Wang, Tao, Kong, Fanxuan, Zhang, Huan, Yi, Jing, Dong, Xiwen, Duan, Han, Tao, Ning, Yang, Yuefeng, Wang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850566/
https://www.ncbi.nlm.nih.gov/pubmed/35229027
http://dx.doi.org/10.1016/j.omto.2022.01.007