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No long-term effects of antenatal synthetic glucocorticoid exposure on epigenetic regulation of stress-related genes

Antenatal synthetic glucocorticoid (sGC) treatment is a potent modifier of the hypothalamic-pituitary-adrenal (HPA) axis. In this context, epigenetic modifications are discussed as potential regulators explaining how prenatal exposure to GCs might translate into persistent changes of HPA axis “funct...

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Detalles Bibliográficos
Autores principales: Müller, Svenja, Moser, Dirk, Frach, Leonard, Wimberger, Pauline, Nitzsche, Katharina, Li, Shu-Chen, Kirschbaum, Clemens, Alexander, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850596/
https://www.ncbi.nlm.nih.gov/pubmed/35173143
http://dx.doi.org/10.1038/s41398-022-01828-x