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Analysis of age-related left ventricular collagen remodeling in living donors: Implications in arrhythmogenesis

Age-related fibrosis in the left ventricle (LV) has been mainly studied in animals by assessing collagen content. Using second-harmonic generation microscopy and image processing, we evaluated amount, aggregation and spatial distribution of LV collagen in young to old pigs, and middle-age and elder...

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Detalles Bibliográficos
Autores principales: García-Mendívil, Laura, Pérez-Zabalza, María, Mountris, Konstantinos, Duwé, Sam, Smisdom, Nick, Pérez, Marta, Luján, Lluís, Wolfs, Esther, Driesen, Ronald B., Vallejo-Gil, José María, Fresneda-Roldán, Pedro Carlos, Fañanás-Mastral, Javier, Vázquez-Sancho, Manuel, Matamala-Adell, Marta, Sorribas-Berjón, Juan Fernando, Bellido-Morales, Javier André, Mancebón-Sierra, Francisco Javier, Vaca-Núñez, Alexánder Sebastián, Ballester-Cuenca, Carlos, Oliván-Viguera, Aida, Diez, Emiliano, Ordovás, Laura, Pueyo, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850748/
https://www.ncbi.nlm.nih.gov/pubmed/35198884
http://dx.doi.org/10.1016/j.isci.2022.103822