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Cerebrospinal fluid p-tau231 as an early indicator of emerging pathology in Alzheimer's disease
BACKGROUND: Phosphorylated tau (p-tau) epitopes in cerebrospinal fluid (CSF) are accurate biomarkers for a pathological and clinical diagnosis of Alzheimer's disease (AD) and are seen to be increased in preclinical stage of the disease. However, it is unknown if these increases transpire earlie...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850760/ https://www.ncbi.nlm.nih.gov/pubmed/35158308 http://dx.doi.org/10.1016/j.ebiom.2022.103836 |