A Novel Compound, Tanshinol Borneol Ester, Ameliorates Pressure Overload-Induced Cardiac Hypertrophy by Inhibiting Oxidative Stress via the mTOR/β-TrCP/NRF2 Pathway

Tanshinol borneol ester (DBZ) exerts anti-atherosclerotic and anti-inflammatory effects. However, its effects on cardiac hypertrophy are not well understood. In this work, we investigated the treatment effects and potential mechanisms of DBZ on the hypertrophic heart under oxidative stress and endop...

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Detalles Bibliográficos
Autores principales: Han, Dongjian, Wang, Fuhang, Wang, Bo, Qiao, Zhentao, Cui, Xinyue, Zhang, Yi, Jiang, Qingjiao, Liu, Miaomiao, Shangguan, Jiahong, Zheng, Xiaohui, Bai, Yajun, Du, Chunyan, Shen, Deliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850779/
https://www.ncbi.nlm.nih.gov/pubmed/35185583
http://dx.doi.org/10.3389/fphar.2022.830763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850779/
https://www.ncbi.nlm.nih.gov/pubmed/35185583
http://dx.doi.org/10.3389/fphar.2022.830763

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