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p53 SUMOylation Mediates AOPP-Induced Endothelial Senescence and Apoptosis Evasion

The aging of endothelial cells plays a critical role in the development of age-related vascular disease. We established a model of endothelial premature senescence by application of Advanced oxidation protein products (AOPPs) modified bovine serum albumin (AOPP-BSA) in human umbilical vein endotheli...

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Detalles Bibliográficos
Autores principales: Chen, Yanjia, Liu, Zhuanhua, Chen, Hongyu, Huang, Xingfu, Huang, Xiaoxia, Lei, Yang, Liang, Qing, Wei, Jiayi, Zhang, Qin, Guo, Xiaohua, Huang, Qiaobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850781/
https://www.ncbi.nlm.nih.gov/pubmed/35187108
http://dx.doi.org/10.3389/fcvm.2021.795747