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TDP-43-associated atrophy in brains with and without frontotemporal lobar degeneration

Transactive response DNA-binding protein of ∼43 kDa (TDP-43), a primary pathologic substrate in tau-negative frontotemporal lobar degeneration (FTLD), is also often found in the brains of elderly individuals without FTLD and is a key player in the process of neurodegeneration in brains with and with...

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Detalles Bibliográficos
Autores principales: Buciuc, Marina, Martin, Peter R., Tosakulwong, Nirubol, Murray, Melissa E., Petrucelli, Leonard, Senjem, Matthew L., Spychalla, Anthony J., Knopman, David S., Boeve, Bradley F., Petersen, Ronald C., Parisi, Joseph E., Reichard, R. Ross, Dickson, Dennis W., Jack, Clifford R., Whitwell, Jennifer L., Josephs, Keith A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850800/
https://www.ncbi.nlm.nih.gov/pubmed/35168140
http://dx.doi.org/10.1016/j.nicl.2022.102954