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Zrsr2 and functional U12-dependent spliceosome are necessary for follicular development

ZRSR2 is a splicing factor involved in recognition of 3′-intron splice sites that is frequently mutated in myeloid malignancies and several tumors; however, the role of mutations of Zrsr2 in other tissues has not been analyzed. To explore the biological role of ZRSR2, we generated three Zrsr2 mutant...

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Detalles Bibliográficos
Autores principales: Gómez-Redondo, Isabel, Pericuesta, Eva, Navarrete-Lopez, Paula, Ramos-Ibeas, Priscila, Planells, Benjamín, Fonseca-Balvís, Noelia, Vaquero-Rey, Aida, Fernández-González, Raúl, Laguna-Barraza, Ricardo, Horiuchi, Keiko, Gutiérrez-Adán, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850803/
https://www.ncbi.nlm.nih.gov/pubmed/35198906
http://dx.doi.org/10.1016/j.isci.2022.103860