Force-dependent remodeling of cytoplasmic ZO-1 condensates contributes to cell-cell adhesion through enhancing tight junctions

The physiological importance of biomolecular condensates is widely recognized, but how it is controlled in time and space during development is largely unknown. Here, we show that a tight junction protein ZO-1 forms cytoplasmic condensates in the trophectoderm (TE) of the mouse embryo before E4.0. T...

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Detalles Bibliográficos
Autores principales: Kinoshita, Noriyuki, Yamamoto, Takamasa S., Yasue, Naoko, Takagi, Chiyo, Fujimori, Toshihiko, Ueno, Naoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850805/
https://www.ncbi.nlm.nih.gov/pubmed/35198899
http://dx.doi.org/10.1016/j.isci.2022.103846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850805/
https://www.ncbi.nlm.nih.gov/pubmed/35198899
http://dx.doi.org/10.1016/j.isci.2022.103846

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