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A Cannabinoid 2-Selective Agonist Inhibits Allogeneic Skin Graft Rejection In Vivo

Previous work from our laboratory showed that a CB2 selective agonist, O-1966, blocked the proliferative response of C57BL/6 mouse spleen cells exposed to spleen cells of C3HeB/FeJ mice in vitro in the mixed lymphocyte reaction (MLR). The MLR is widely accepted as an in vitro correlate of in vivo gr...

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Detalles Bibliográficos
Autores principales: Jayarajan, Senthil, Meissler, Joseph J., Adler, Martin W., Eisenstein, Toby K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850832/
https://www.ncbi.nlm.nih.gov/pubmed/35185546
http://dx.doi.org/10.3389/fphar.2021.804950