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Induction of Anti-Proliferative and Apoptotic Effects of Sorafenib Using miR-27a Inhibitor in Hepatocellular Carcinoma Cell Lines

OBJECTIVE: The purpose of the current study was to investigate the possible anti-tumor effect of miR-27a inhibitor in combination with Sorafenib (SOR) on cell proliferation and apoptosis of hepatocellular carcinoma cell lines. METHODS: Transient transfection by oligo-miR27a inhibitor (miR-27ai) was...

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Detalles Bibliográficos
Autores principales: Abdel Wahab, Abdel Hady A, Ayad, Eman G, Abdulla, Mohga S, Sharada, Hayat M, Ashmawy, Abeer M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850906/
https://www.ncbi.nlm.nih.gov/pubmed/34582667
http://dx.doi.org/10.31557/APJCP.2021.22.9.2951