Cargando…

Induction of Anti-Proliferative and Apoptotic Effects of Sorafenib Using miR-27a Inhibitor in Hepatocellular Carcinoma Cell Lines

OBJECTIVE: The purpose of the current study was to investigate the possible anti-tumor effect of miR-27a inhibitor in combination with Sorafenib (SOR) on cell proliferation and apoptosis of hepatocellular carcinoma cell lines. METHODS: Transient transfection by oligo-miR27a inhibitor (miR-27ai) was...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abdel Wahab, Abdel Hady A, Ayad, Eman G, Abdulla, Mohga S, Sharada, Hayat M, Ashmawy, Abeer M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	West Asia Organization for Cancer Prevention 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850906/ https://www.ncbi.nlm.nih.gov/pubmed/34582667 http://dx.doi.org/10.31557/APJCP.2021.22.9.2951

Ejemplares similares

Urinary high molecular weight matrix metalloproteinases as non-invasive biomarker for detection of bladder cancer
por: Mohammed, Mohammed A, et al.
Publicado: (2013)

Novel combination of sorafenib and biochanin-A synergistically enhances the anti-proliferative and pro-apoptotic effects on hepatocellular carcinoma cells
por: Youssef , Mohieldin M., et al.
Publicado: (2016)

Circulating MiR-210 and MiR-1246 as Potential Biomarkers for Differentiating Hepatocellular Carcinoma from Metastatic Tumors in the Liver
por: Ahmed, Emad K., et al.
Publicado: (2019)

Combination Therapy of TRAIL and Thymoquinone Induce Breast Cancer Cell Cytotoxicity-Mediated Apoptosis and Cell Cycle Arrest
por: Abdel Salam, Nagwa M, et al.
Publicado: (2021)

Possible Use of miR-223-3p as a Prognostic Marker in Transarterial Chemoembolization Treatment of Hepatocellular Carcinoma Patients
por: Abdelaziz, Heba E., et al.
Publicado: (2022)

Novel Combination of Sorafenib and Celecoxib Provides Synergistic Anti-Proliferative and Pro-Apoptotic Effects in Human Liver Cancer Cells
por: Cervello, Melchiorre, et al.
Publicado: (2013)

Antioxidant activity and apoptotic induction as mechanisms of action of Withania somnifera (Ashwagandha) against a hepatocellular carcinoma cell line
por: Ahmed, Wafaa, et al.
Publicado: (2018)

Lymphocyte to monocyte ratio predicts survival and is epigenetically linked to miR-222-3p and miR-26b-5p in diffuse large B cell lymphoma
por: Metwally, Ayman Mohamed, et al.
Publicado: (2023)

Yttrium-90 resin microspheres as an adjunct to sorafenib in patients with unresectable hepatocellular carcinoma
por: Mahvash, Armeen, et al.
Publicado: (2016)

Effects of miR-193a and sorafenib on hepatocellular carcinoma cells
por: Salvi, Alessandro, et al.
Publicado: (2013)

Therapeutic role of mesenchymal stem cells and platelet-rich plasma on skin burn healing and rejuvenation: A focus on scar regulation, oxido-inflammatory stress and apoptotic mechanisms
por: Tammam, Bakinam M.H., et al.
Publicado: (2023)

SLC27A5 promotes sorafenib-induced ferroptosis in hepatocellular carcinoma by downregulating glutathione reductase
por: Xu, Feng-li, et al.
Publicado: (2023)

Self-Nanoemulsifying Drug Delivery System of 2-Methoxyestradiol Exhibits Enhanced Anti-Proliferative and Pro-Apoptotic Activities in MCF-7 Breast Cancer Cells
por: Al-Qahtani, Salwa D., et al.
Publicado: (2022)

Development of 2-oindolin-3-ylidene-indole-3-carbohydrazide derivatives as novel apoptotic and anti-proliferative agents towards colorectal cancer cells
por: Eldehna, Wagdy M., et al.
Publicado: (2020)

miR-222 regulates sorafenib resistance and enhance tumorigenicity in hepatocellular carcinoma
por: Liu, Kai, et al.
Publicado: (2021)

The Proliferative and Apoptotic Landscape of Basal-like Breast Cancer
por: Alexandrou, Sarah, et al.
Publicado: (2019)

Investigating the Pretreatment miRNA Expression Patterns of Advanced Hepatocellular Carcinoma Patients in Association with Response to TACE Treatment
por: El-Halawany, Medhat S., et al.
Publicado: (2015)

Novel coumarin-6-sulfonamides as apoptotic anti-proliferative agents: synthesis, in vitro biological evaluation, and QSAR studies
por: Sabt, Ahmed, et al.
Publicado: (2018)

The Antioxidant, Anti-Apoptotic, and Proliferative Potency of Argan Oil against Betamethasone-Induced Oxidative Renal Damage in Rats
por: Orabi, Sahar Hassan, et al.
Publicado: (2020)

DNA Methylation of TGFβ Target Genes: Epigenetic Control of TGFβ Functional Duality in Liver Cancer
por: Bévant, Kevin, et al.
Publicado: (2021)

Apoptotic Cell Death and the Proliferative Capacity of Human Breast Cancers
por: Losa, Gabriele A., et al.
Publicado: (1998)

Sorafenib Rechallenge and Sorafenib after Lenvatinib Failure in a Patient with Hepatocellular Carcinoma
por: Ikeda, Atsuyuki, et al.
Publicado: (2021)

Anti-Proliferative and Pro-Apoptotic Effects of Calligonum comosum (L’Her.) Methanolic Extract in Human Triple-Negative MDA-MB-231 Breast Cancer Cells
por: Alehaideb, Zeyad, et al.
Publicado: (2020)

Sorafenib in the Treatment of Advanced Hepatocellular Carcinoma
por: Mousa, Ali Ben
Publicado: (2008)

Sorafenib for the treatment of unresectable hepatocellular carcinoma
por: Furuse, Junji
Publicado: (2008)

Sorafenib Effectiveness in Advanced Hepatocellular Carcinoma
por: Sanoff, Hanna K., et al.
Publicado: (2016)

MiR-122 Targets SerpinB3 and Is Involved in Sorafenib Resistance in Hepatocellular Carcinoma
por: Turato, Cristian, et al.
Publicado: (2019)

Synthesis of new oxadiazol-phthalazinone derivatives with anti-proliferative activity; molecular docking, pro-apoptotic, and enzyme inhibition profile
por: Hekal, Mohamed H., et al.
Publicado: (2020)

Thymoquinone Crosstalks with DR5 to Sensitize TRAIL Resistance and Stimulate ROS-Mediated Cancer Apoptosis
por: Abd-Rabou, Ahmed A, et al.
Publicado: (2021)

Hyperacute versus Subacute Coiling of Aneurysmal Subarachnoid Hemorrhage a Short-term Outcome and Single-Center Experience, Pilot Study
por: Ibrahim Ali, Abdulrahman Mostafa, et al.
Publicado: (2016)

Regulation of cell death receptor S-nitrosylation and apoptotic signaling by Sorafenib in hepatoblastoma cells()
por: Rodríguez-Hernández, A., et al.
Publicado: (2015)

Effect of a waste management intervention program on knowledge, attitude, and practice (KAP) of nurses and housekeepers: a quasi-experimental study, Egypt
por: Khashaba, Eman, et al.
Publicado: (2023)

Interleukin-27 augments the inhibitory effects of sorafenib on bladder cancer cells
por: Cao, J.Y., et al.
Publicado: (2017)

Anti-proliferative and pro-apoptotic effects of GHRH antagonists in prostate cancer
por: Muñoz-Moreno, Laura, et al.
Publicado: (2016)

BRCA1 expression, proliferative and apoptotic activities in ovarian epithelial inclusions
por: Wang, Yiying, et al.
Publicado: (2017)

Knockdown of CD-74 in the Proliferative and Apoptotic Activity of Breast Cancer Cells
por: Ssadh, Hussain Al, et al.
Publicado: (2019)

Exosomal MiR-744 Inhibits Proliferation and Sorafenib Chemoresistance in Hepatocellular Carcinoma by Targeting PAX2
por: Wang, Guanghui, et al.
Publicado: (2019)

Cerebrovascular Accidents Associated with Sorafenib in Hepatocellular Carcinoma
por: Saif, Muhammad W., et al.
Publicado: (2011)

Safety and efficacy of sorafenib in the treatment of hepatocellular carcinoma
por: Almhanna, Khaldoun, et al.
Publicado: (2009)

Evolving role of Sorafenib in the management of hepatocellular carcinoma
por: Ziogas, Ioannis A, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_och74l58ju3bm81gfhg6f63ge7