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HLA-C*04:01 Affects HLA Class I Heterozygosity and Predicted Affinity to SARS-CoV-2 Peptides, and in Combination With Age and Sex of Armenian Patients Contributes to COVID-19 Severity

The novel SARS-CoV-2 coronavirus infection has become a global health concern, causing the COVID-19 pandemic. The disease symptoms and outcomes depend on the host immunity, in which the human leukocyte antigen (HLA) molecules play a distinct role. The HLA alleles have an inter-population variability...

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Detalles Bibliográficos
Autores principales: Hovhannisyan, Anahit, Madelian, Vergine, Avagyan, Sevak, Nazaretyan, Mihran, Hyussyan, Armine, Sirunyan, Alina, Arakelyan, Rubina, Manukyan, Zorayr, Yepiskoposyan, Levon, Mayilyan, Karine R., Jordan, Frieda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850920/
https://www.ncbi.nlm.nih.gov/pubmed/35185875
http://dx.doi.org/10.3389/fimmu.2022.769900