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Macrophage Membrane-Camouflaged shRNA and Doxorubicin: A pH-Dependent Release System for Melanoma Chemo-Immunotherapy

Improving the efficacy of melanoma treatment remains an important global challenge. Here, we combined chemotherapy with protein tyrosine phosphatase nonreceptor type 2(Ptpn2) based immunotherapy in an effort to address this challenge. Short-hairpin RNA (shRNA) targeting Ptpn2 was coencapsulated with...

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Detalles Bibliográficos
Autores principales: Yang, Chengli, Ming, Yang, Zhou, Kai, Hao, Ying, Hu, Danrong, Chu, Bingyang, He, Xinlong, Yang, Yun, Qian, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851070/
https://www.ncbi.nlm.nih.gov/pubmed/35233535
http://dx.doi.org/10.34133/2022/9768687