Expanded substrate specificity supported by P1′ and P2′ residues enables bacterial dipeptidyl-peptidase 7 to degrade bioactive peptides

Dipeptide production from extracellular proteins is crucial for Porphyromonas gingivalis, a pathogen related to chronic periodontitis, because its energy production is entirely dependent on the metabolism of amino acids predominantly incorporated as dipeptides. These dipeptides are produced by perip...

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Detalles Bibliográficos
Autores principales: Ohara-Nemoto, Yuko, Shimoyama, Yu, Ono, Toshio, Sarwar, Mohammad Tanvir, Nakasato, Manami, Sasaki, Minoru, Nemoto, Takayuki K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851246/
https://www.ncbi.nlm.nih.gov/pubmed/35032549
http://dx.doi.org/10.1016/j.jbc.2022.101585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8851246/
https://www.ncbi.nlm.nih.gov/pubmed/35032549
http://dx.doi.org/10.1016/j.jbc.2022.101585

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